Dissimilar Effects of Tolterodine on Detrusor Overactivity in Awake Rats with Chemical Cystitis and Partial Bladder Outlet Obstruction
نویسندگان
چکیده
منابع مشابه
Dissimilar Effects of Tolterodine on Detrusor Overactivity in Awake Rats with Chemical Cystitis and Partial Bladder Outlet Obstruction
PURPOSE We investigated bladder function, with a special focus on nonvoiding contractions (NVCs), in awake rats with chronic chemical cystitis and bladder outlet obstruction (BOO) by use of simultaneous registrations of intravesical and intraabdominal pressures. In addition, we tested the effects of tolterodine on the NVCs in these models. METHODS A total of 20 female Sprague-Dawley rats were...
متن کاملAB259. TRPV1 receptor associated with detrusor overactivity induced by partial bladder outlet obstruction in rats
© Translational Andrology and Urology. All rights reserved. Transl Androl Urol, 2016;5(S1) tau.amegroups.com Compared with the control group, the quantity of MDA was increased and the activities of SOD and GSH-Px were decreased in diabetic group (P<0.05) while GSPE could reverse the changes of MDA, SOD and GSH-Px. Conclusions: GSPE could ameliorate diabetic bladder dysfunction which may be asso...
متن کاملRole of Nicotinic Acetylcholine Receptor α3 and α7 Subunits in Detrusor Overactivity Induced by Partial Bladder Outlet Obstruction in Rats
PURPOSE To investigate the role of α3 and α7 nicotinic acetylcholine receptor subunits (nAChRs) in the bladder, using a rat model with detrusor overactivity induced by partial bladder outlet obstruction (BOO). METHODS Forty Sprague-Dawley rats were used: 10 were sham-operated (control group) and 30 were observed for 3 weeks after partial BOO. BOO-induced rats were further divided into 3 group...
متن کاملNear-Normalized Gene Expression Profiles in Bladder With Detrusor Overactivity in Rats With Bladder Outlet Obstruction After Deobstruction
PURPOSE The pathophysiological role of detrusor overactivity (DO) in the bladder, which is commonly observed in various bladder diseases, is not well understood. DO appears in bladder outlet obstruction (BOO), and may continue even after subsequent deobstruction. DO therefore provides an excellent opportunity to observe molecular biological changes. METHODS In this study, to understand the mo...
متن کاملAB099. Improvement of persistent detrusor overactivity after relief of bladder outlet obstruction treated by phytotherapeutic agent
© Translational Andrology and Urology. All rights reserved. Transl Androl Urol, 2017;6(S3) tau.amegroups.com (P<0.05). ESWT can promote proliferation of endothelial cells in corpus cavernosum. The result was significantly higher in the ESWT group than in the DMED group (P<0.05). ESWT can improve cell metabolism in vivo. The expression of mitochondrial membrane proteins is higher in the ESWT gro...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Neurourology Journal
سال: 2011
ISSN: 2093-6931
DOI: 10.5213/inj.2011.15.3.120